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Ginseng: A Glycemic Reduction Factor!
Bill Bailey, Ph.D., MH, ND, CNHP, CTN
(Dr. Bailey can be reached at Traditional Naturopath) |
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Ginseng is
widely known as a beneficial herb, with many healthful attributes
attributed to its regular use. "Ginseng increases resistance to
the effects of stress and improves circulation and mental functioning.
Health conditions contributed to be stress include increased acidity of
the body chemistry, back pain, cancer, Crohn's disease (inflammation of
the intestinal tract), depression, chronic diarrhea, digestive
disorders, hair loss, headaches, hypertension or high blood pressure,
impotence, insomnia, TMJ syndromes (jaw pain and clicking), nervous and
anxiety disorders, obsessive compulsive behaviors, various skin
conditions, and finally, ulcers. Ginseng, whether it comes from Korea or
Minnesota, is for people who have chronic fever, thirst, hot flashes,
people who crave excess sweets and have excess hunger." (Benefits
of Ginseng, Megaton Article, emphasis mine.) This last benefit can
be a definite benefit to dieters! In fact, ginseng usage has been shown
to result in "reduced glycemia in both non-diabetic subjects and
Type II diabetes suffers given the herb 40 minutes prior to a glucose
challenge" (Vulsan, V et al. Arch Inter Med
160(7):1009-1013, 2000.) Furthermore, the article, The Benefits of
Ginseng, states: "Dried ginseng root may help people with type 2
diabetes control blood sugar levels. One study showed that in the
diabetics, ginseng lowered blood sugar 20% more than placebo pills.
Among those who did not have diabetes, there was also a similar drop in
blood sugar levels." This drop in blood sugar levels could benefit
low carbohydrate dieters by lowering overall blood sugar, thus
preventing the release of the fat storing hormone, insulin.
"There are many "ginsengs" on the market, but the two main species of
ginseng are Panax ginseng (Asian) and Panax quinquefolius
(American). Although it is a member of the same Araliaceae family as
ginseng, Eleutherococcus senticosus (Siberian ginseng) is not
true ginseng but a distant relative of the panax species. Siberian
ginseng has different active ingredients, yet has similar benefits as
panax ginseng, thereby the confusion.
Panax is Latin
for 'all-healing,' which is how the Chinese have considered the herb for
thousands of years. As such, it is also known as an adaptogen, as it
helps the body adapt to various potentially detrimental conditions.
Panax has been credited with many healthy actions including helping to
resist stress, increase longevity, strengthen immunity, relieve insomnia
and depression, balance blood-sugar levels, increase energy and
endurance, as well as to improve memory, alertness, concentration and
spirit.
Asian ginseng
is native to Northern China and both North and South Korea and has been
considered by Chinese doctors as the foremost herb in Traditional
Chinese Medicine (TCM). American ginseng grows in North America from
Canada to Louisiana and was praised by Native Americans before the
settlers came. Even Asians applauded American ginseng that was imported
in the 1700s. Nevertheless, Asian ginseng is the most popular species of
ginseng and, despite its origins, the majority of the herb is now grown
commercially in the United States, though Canada, China, North and South
Korea, Russia and Japan also grow and export the herb.
The most used
portion of ginseng is the root, which resembles a human being. The
primary active constituents are complex carbohydrates called saponins or
ginsenosides, thirteen of which have been identified in Asian ginseng.
Each ginsenoside is thought to have its own action or benefit, further
enacting the 'all-healing' moniker ginseng enjoys. The two species of
Panax ginseng vary in terms of type and ratio of ginsenosides. The
amount of ginsenosides in any given portion of ginseng is dependent upon
numerous factors, including the species, area of cultivation and the
quality of ginseng grown. Also, it is reported that the older the
ginseng plant, the higher the potency.
How the herb is
processed can have a great effect on its potency. White ginseng is the
natural, unprocessed root. Red ginseng is root that is processed by
steaming and heating. Because such processes can be hard to withstand,
only older and more potent ginseng roots undergo this treatment, leading
to claims that red ginseng is more potent than white. Wild ginseng is
the natural form of the entire ginseng plant. Such ginseng is rare in
Asia, but the American species is more abundant (although harvesting is
strictly controlled by various state and provincial officials in North
America.)
Asian ginseng
has been more frequently studied by researchers, who have focused
largely on ginsenosides Rg1 and Rb1. Most of the scientific attention on
ginseng has been in the areas of immunity, cancer prevention, heart
disease prevention, neurology, stress resistance and protection from
radiation.
A study in
India involved two groups of rats injected with a fatal virus. One group
received ginseng for 5.5 days prior to injection and for 3.5 days
following injection; the other group received no ginseng. Researchers
reported that 35 percent of the rats given ginseng survived the virus,
while all other rats perished. Moreover, scientists later found that the
surviving rats had developed an immunity to the virus after the ginseng
supplementation.
South Korean
researchers gave each of two groups of 100 mice a different carcinogen
(cancer-causing substance) and gave another two groups of mice the same
carcinogens plus ginseng. After 6 to 12 months of supplementation, the
ginseng groups showed significantly fewer and smaller tumors per mouse
than did the groups not receiving ginseng. These results were
reconfirmed in another South Korean study, in which 20 mice receiving a
carcinogen and ginseng had fewer and smaller tumor than did 20 mice
receiving the carcinogen but no ginseng. Further cancer protection by
ginseng was shown in a Hong Kong study that involved Rg3 ginsenosides
and human prostate carcinoma cells. Researchers reported that Rg3
inhibited growth of the carcinoma by inducing apoptosis, or cell death
(Liu, W. et al. Life Sci 67(11):1297-306, 2000).
As for
ginseng's heart health benefits, Japanese researchers reported that a
ginseng extract given orally to rats reduced serum total cholesterol and
triglycerides that lead to fatty liver (Cui, X et al. J Int Med Res
26(4):181-7, 1998). The results were reportedly related to dose amounts,
with the best results in the 125- to 250-mg range of supplementation.
A series of
Japanese studies showed that mice given a lethal dose of radiation as
well as injections of purified ginseng extract had higher survival rates
than their similarly irradiated counterparts who received no ginseng.
Researchers noted that the mice taking the largest doses of ginseng had
the highest rates of survival, 82 percent. Mice receiving only radiation
and a saline solution did not survive.
Beyond these
research areas, ginseng has shown additional benefits.
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Rg1 and Rb1
ginsenosides have been shown to enhance endurance in rats (Wang, L.
and Lee, T. Planta Med 64(2):130-3, 1998);
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American
ginseng has demonstrated the ability to stimulate coital behavior in
rats (Murphy, L et al. Physiol Behav 64(4):445-50, 1998);
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A saponin
extract from ginseng showed an ability to enhance sperm motility
(Chen, J et al. Phytomed 5(4):289-92, 1998); and
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American
ginseng reduced glycemia in both non-diabetic subjects and Type II
diabetes suffers given the herb 40 minutes prior to a glucose
challenge (Vulsan, V et al. Arch Inter Med 160(7):1009-1013,
2000).
The science of
ginseng and its various healthy actions is ongoing, with future results
sure to further define the herbs wide-reaching effects. As such, doses
of ginseng will vary, but the average dose recommended by experts ranges
from 25 to 75 mg of ginsenosides per day. This can be determined by
multiplying the capsule, tablet or drop dose by the percentage of
ginsenosides to which the extract is standardized. For whole root
consumption, average doses vary from 500 mg to 6,000 mg of root per day.
Ginseng is
widely considered a safe herb, but massive overdose can lead to Ginseng
Abuse Syndrome, which is marked by insomnia and extreme muscular or
arterial. Persons with high blood pressure should avoid ginseng use, as
should pregnant or lactating women." (HSR Magazine Report, Ginseng,
December 2000)
Other benefits in ginseng use are:
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Strengthening the body
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Improving memory
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Increasing vitality
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Extending endurance
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Cleansing the body of
stress
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Fighting fatigue
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Resisting disease
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Bolstering immunity
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Balancing metabolism
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Preventing headaches
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Treating sleep disorders
and overcoming insomnia
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Ginseng has had beneficial
effects on women suffering post-menopausal symptoms.
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Ginseng has also
demonstrated clinical improvements in virility among men, and
effected improvements in conditions of sexual dysfunction for both
sexes.
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